Scientist IV ( {{city}}) Job at Advanced Clinical, Ridgefield, CT

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  • Advanced Clinical
  • Ridgefield, CT

Job Description

We are seeking a highly skilled Solid State NMR Spectroscopist to join our Material & Analytical Sciences team. This is an excellent opportunity to work with cutting-edge technology, expand scientific expertise, and gain insight into the drug development process.

Key Responsibilities

  • Acquire and interpret 1D & 2D multinuclear ssNMR data (H, C, N, F, etc.) for structure elucidation.
  • Characterize pharmaceutical materials (particles, powders, suspensions, APIs, excipients, intermediates, and drug products).
  • Apply quantitative ssNMR methods to analyze components in APIs and drug products.
  • Combine ssNMR with complementary techniques (e.g., X-ray crystallography, molecular modeling) for 3D structural evaluation.
  • Troubleshoot ssNMR experiments and manage data backup/retrieval.
  • Prepare technical reports, present findings, and contribute to cross-functional teams.
  • Stay current with scientific literature to design and implement innovative experiments.

Requirements (Must-Haves)

  • Masters/Ph.D. in Organic Chemistry (or equivalent) with 13 years of ssNMR experience applied to small molecules.
  • Hands-on expertise in solid-state NMR sample prep, acquisition, and interpretation.
  • Proficiency in implementing/troubleshooting ssNMR experiments and changing Bruker probes.
  • Strong knowledge of molecular structures, interactions, and conformational effects.
  • Ability to work independently and collaboratively, with excellent communication and organizational skills.

Preferred Skills (Nice-to-Haves)

  • Background in solution NMR for structure elucidation.
  • Experience applying ssNMR to biological systems (proteins, membrane proteins).
  • Familiarity with computational chemistry & molecular modeling tools (Gaussian, Schrdinger, Materials Studio, CCDC).
  • Experience with HPC clusters & Linux environments.
  • Strong track record of presenting results and collaborating in multidisciplinary teams.

Job Tags

Part time,

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